Instrumentation

The Department of Chemistry has a wise array of instruments. They are housed in De La Roche 315, next door to the Chemistry Research Lab and down the hall from the Chemistry Suite.

Nuclear Magnetic Resonance Spectrometer

Organic Chemistry students use the NMR extensivelyThe largest of the new instruments is a Nuclear Magnetic Resonance Spectrometer. The instrument, which everyone refers to as the "NMR", is a JEOL ECS 400.

An NMR is commonly used in determining chemical structures, understanding chemical and enzyme kinetics, determining protein structures, and in a variety of other chemical, physical, and biological applications. It is the standard tool for chemical characterization in industry, academics, and government. An NMR works on the same principles as MRI (magnetic resonance imaging) through exciting atoms to understand their unique environment. The spectrometer is a complex system which, at its core, utilizes a superconducting magnet kept at -459 degrees F through cooling with liquid helium and liquid nitrogen. Our 400 MHz high field NMR is ahead of research standards (for now), has automation power to run countless experiments on 24 different samples in succession, and uses a revolutionary software called Delta which is user-friendly even for beginners.

For a chemistry major at St. Bonaventure, training on the NMR begins as a sophomore in Organic Chemistry I (CHEM 301 & (CHML 301). In the photo above, Dr. David Hilmey (left, front) instructs Organic Chem students on the use the NMR. After training, students use the instrument themselves, at times without direct supervision. Extensive use of the NMR continues in Physical Chemistry II (CHEM 402 & CHML 402) as well as Instrumental Analysis (CHEM 431 & CHML 431). It also finds frequent use in the ongoing research by the Chemistry Department faculty.

NEW: Glove Box

Our MBraun Unilab Glove Box was installed in 2012 and allows for our faculty and student researchers to work in atmospheres free of oxygen for highly unstable materials and complexes. Both Dr. Brestensky and Dr. Arumugam use the glove box in their research with metal complexes.

NEW: Fluorimeter

The Olis ArcOptix fluorimeter measures the fluorescence emissions of given substances and chemical compounds at seven different wavelengths. When a molecule is excited with light, sometimes the molecule will emit a different wavelength of light. This is fluorescence and a fluorimeter can quantify this light emission. Applications are found in medicine, biochemistry, and forensics.

NEW: Raman Spectrophotometer

The DeltaNu Raman spectrometer is used to observe vibrational, rotational, and other low frequency modes of excitation and is complementary to our infrared spectrometer. Raman is commonly used for analysis of crystals to determine morphology and packing. It is also used in the monitoring of anesthetics during surgery and in the field of nanotechnology for analyzing nanostructures such as nanocrystals, nanotubes, and graphene.

FT- Infrared Spectrophotometer

Our Nicolet Nexus 670 FT-IR allows us to excite specific chemical bonds to determine structure or identify compounds by their characteristic IR “fingerprint”. Our instrument also allows for ATR sampling which results in very simple sample preparation. Students can expect to work on this instrument by their sophomore year. It is often used in manufacturing for quality control, in plastics analysis, and in forensics, such as to measure blood alcohol content.

Inductively-Coupled Plasma Mass Spectrometer

Inductively Coupled Plasma Mass Spectrometer

The ICP-MS is a sensitive analytical device used in elemental analysis, capable of part-per-billion sensitivity. A sample is broken into ions by passing through a "torch" made of Argon cations and free electrons with a temperature of approximately 10,000 degrees Celsius. The ions are then identified by mass by a quadrupole mass spectrometer. This technique can be applied to a wide variety of sample types, but is particularly well-suited for trace metal analysis.

Liquid Chromatography Mass Spectrometer

Tandem Liquid Chromatography Mass SpectrometerThe LC-MS is a powerful instrument that combines the physical separation capabilities of high performance liquid chromatography (HPLC) with the mass analysis capabilities of mass spectrometry. The LC-MS is standard equipment in the pharmaceutical and chemical industry. It's important in quality control, drug development, as well as testing the pharmacokinetics of drugs to see how quickly it is cleared from the body. It has also been used extensively in proteomics, the follow-up field of study to the sequencing of the human genome.

  

Gas Chromatography Mass Spectrometer

The LC-MS, described above, complements our previously-obtained GC-MS. The GC-MS is very important in identifying substances in environmental chemistry, forensics, astro-chemistry, food analysis, and medicine.

Ultraviolet-Visible Spectrophotometer

Chemistry students putting a sample in the UV-VisThe UV-Vis measures the ability of molecules to absorb light photons at a particular wavelength in the ultraviolet or visible region. This is often used to measure oxidation states of metals, conjugation in organic molecules, and charge transfer between two or more different molecules.